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Applications of intelligent technology in the evaluation of mutagenicity.
Li, Jia; Xu, Wenli; Zhang, Wenchao; Liu, Dingjin; Jiang, Shuyang; Liu, Guohua; Wang, Yong; Sun, Haoran; Xu, Wenping; Jiang, Biao; Yao, Jianhua.
Afiliação
  • Li J; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Xu W; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Zhang W; Zhengzhou University of Technology, Zhengzhou, Henan Province 450044, China.
  • Liu D; Zhengzhou University of Technology, Zhengzhou, Henan Province 450044, China.
  • Jiang S; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Liu G; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Wang Y; Zhengzhou University of Technology, Zhengzhou, Henan Province 450044, China.
  • Sun H; Zhengzhou University of Technology, Zhengzhou, Henan Province 450044, China.
  • Xu W; School of Pharmaceutical, East China University of Science and Technology, Shanghai 200237, China.
  • Jiang B; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China. Electronic address: jiangb@mail.sioc.ac.cn.
  • Yao J; Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials (Chinese Academy of Sciences), Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China; Zhengzhou University of Technology, Zhengzhou, Henan Province 450044, China. Electronic address: yaojh
Mutat Res Genet Toxicol Environ Mutagen ; 897: 503785, 2024 Jul.
Article em En | MEDLINE | ID: mdl-39054008
ABSTRACT
Bioassays are widely used in assessment of mutagenicity. Alternative methods have also been developed, including "intelligent evaluation", which depends on the quality of data, strategies, and techniques. CISOC-PSMT is an Ames test prediction system. The strategies and techniques for intelligent evaluation and four applications of CISOC-PSMT are presented; roles in pesticide management, environmental protection, drug discovery, and safety management of chemicals are introduced.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Mutagenicidade / Mutagênicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Mutagenicidade / Mutagênicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article