Targeting Food Allergy with Probiotics.
Adv Exp Med Biol
; 1449: 79-93, 2024.
Article
em En
| MEDLINE
| ID: mdl-39060732
ABSTRACT
The globally dramatic increase in food allergy prevalence and severity is demanding effective preventive and therapeutic strategies. Food allergy derives from a defect of immune tolerance mechanisms. Immune tolerance is modulated by gut microbiome composition and function, and gut microbiome dysbiosis has been associated with the development of food allergy. Selected probiotic strains could regulate immune tolerance mechanisms. The mechanisms are multiple and are still not completely defined. Increasing evidence is providing useful information on the choice of optimal bacterial species/strains, dosage, and timing for intervention. The increased knowledge on the crucial role played by postbiotic gut microbiome-derived metabolites, such as butyrate, is also opening the way to a post- biotic approach in the stimulation of immune tolerance.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Probióticos
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Disbiose
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Microbioma Gastrointestinal
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Hipersensibilidade Alimentar
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Tolerância Imunológica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article