Latest from the WISE: Contributions to the Understanding of Ischemia and Heart Failure among Women with No Obstructive Coronary Arteries.

Hansen, Breanna; Nelson, Michael D; Handberg, Eileen M; Pepine, Carl J; Bairey Merz, C Noel; Wei, Janet.

Afiliação

Hansen B; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Nelson MD; Department of Kinesiology, University of Texas at Arlington, Arlington, TX 76019, USA.
Handberg EM; Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL 32611, USA.
Pepine CJ; Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL 32611, USA.
Bairey Merz CN; Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Wei J; Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Rev Cardiovasc Med ; 24(3): 90, 2023 Mar.

Article em En | MEDLINE | ID: mdl-39077501

ABSTRACT

Since 1996, the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) has been investigating pathophysiological processes underlying ischemic heart disease in women and related outcomes. Recent findings have focused on women with signs and symptoms of ischemia and no obstructive coronary arteries (INOCA) and their elevated risk for heart failure with preserved ejection fraction (HFpEF). This review summarizes the latest WISE findings related to INOCA and pre-HFpEF characteristics, addressing our understanding of contributions from traditional vs nontraditional risk factors in women.

Palavras-chave

cardiac magnetic resonance; coronary microvascular dysfunction; heart failure with preserved ejection fraction; ischemic heart disease; women

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article