Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Overlap Syndrome: An Update on the Epidemiology, Pathophysiology, and Management.
Sleep Med Clin
; 19(3): 405-417, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-39095139
ABSTRACT
This review provides an up-to-date summary of the prevalence, pathophysiology, diagnosis, and treatment of the chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) overlap syndrome (OVS). The presence of OVS is high in patients with COPD and in patients with OSA and is associated with profound nocturnal oxygen desaturation and systemic inflammation. There is a high prevalence of cardiovascular disease among patients with OVS and this likely contributes to increased mortality. Observational studies suggest that positive airway pressure therapy improves survival and reduces COPD exacerbations; however, randomized controlled trials will be required to confirm these findings.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apneia Obstrutiva do Sono
/
Doença Pulmonar Obstrutiva Crônica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article