In Silico Assessment of LIR Motif-Containing Proteins Binding to ATG8-Family Proteins.
Methods Mol Biol
; 2845: 197-201, 2024.
Article
em En
| MEDLINE
| ID: mdl-39115668
ABSTRACT
Selective autophagic degradation of cellular components has been shown to be mediated by the interaction of LIR motif-containing proteins with ATG8-family proteins. Here, we present a detailed methodology for the in silico evaluation of potential binding between LIR motif-containing proteins and ATG8-family proteins. We visualize AlphaFold-predicted protein complexes using PyMOL to assess potential interactions, providing an effective computational tool for this purpose.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ligação Proteica
/
Família da Proteína 8 Relacionada à Autofagia
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article