Photoredox-catalyzed C(sp2)-H trifluoromethylation of 3-methylene-isoindolin-1-ones under metal-free conditions.
Org Biomol Chem
; 22(34): 6928-6932, 2024 Aug 28.
Article
em En
| MEDLINE
| ID: mdl-39119751
ABSTRACT
A facile synthetic method for direct C(sp2)-H bond trifluoromethylation of 3-methylene-isoindolin-1-ones under visible-light-induced metal-free conditions is presented. This protocol features mild reaction conditions, broad substrate scope and excellent functional group tolerance, resulting in a range of structurally diverse trifluoromethylated products in good to excellent yields.
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MEDLINE
Idioma:
En
Ano de publicação:
2024
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Article