Reducing Capillary Leak Syndrome Mortality in Extremely Premature Infants: A Pilot Investigation.
Clin Pediatr (Phila)
; : 99228241272037, 2024 Aug 09.
Article
em En
| MEDLINE
| ID: mdl-39123307
ABSTRACT
Neonatal capillary leak syndrome (CLS) is a rare, but life-threatening condition following neonatal sepsis or inflammatory injury. The objective of this study was to describe a standardized treatment approach for CLS that improves mortality and neonatal outcomes. A retrospective cohort study of 10 infants born at 22 to 26 weeks of gestation who developed CLS following a significant inflammatory insult was performed. Time to diagnosis and treatment approaches over 2 epochs were recorded and described. In epoch 2, with increased clinical awareness of CLS and implementation of a standardized treatment approach, there was a non-statistically significant decrease in the time to treatment with a significant decrease in mortality. An early targeted treatment approach for neonatal CLS can decrease mortality rates in this highly morbid condition.
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MEDLINE
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En
Ano de publicação:
2024
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Article