Epicardial adipose tissue thickness associated with preeclampsia and birth weight in early pregnancy.
Hypertens Pregnancy
; 43(1): 2390531, 2024 Dec.
Article
em En
| MEDLINE
| ID: mdl-39129211
ABSTRACT
OBJECTIVE:
Preeclampsia (PE) increases the risk of many adverse maternal and fetal outcomes. This study was to investigate the correlation between epicardial adipose tissue (EAT) thickness and PE and birth weight.METHODS:
This was a single-center retrospective study, 221 patients with PE were selected, and 81 women without hypertension and proteinuria were selected as a comparison. Echocardiogram was performed in their first prenatal examinations at 11-13 gestational weeks, and the thickness of EAT was measured. At the subsequent follow-up, the birth weight was recorded.RESULTS:
EAT thickness was significantly elevated (6.60 ± 1.34 vs. 5.71 ± 1.79 mm, p < 0.001) in severe PE compared to mild PE. In the multivariate analysis, EAT thickness (OR 5.671, 95% CI, 1.991-16.150, p = 0.001), and C reactive protein (OR 4.097, 95% CI, 2.323-7.224, p < 0.001) were found as significant independent predictors of severe PE after adjusting for other risk factors. Linear regression analysis showed that hs-CRP, EAT thickness, and severe PE significantly negatively affected birth weight.CONCLUSION:
EAT thickness can be used to identify pregnant women with severe PE risks and low birth weight. It is an independent risk factor for severe PE but is not a valuable sign of mild PE.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pericárdio
/
Pré-Eclâmpsia
/
Peso ao Nascer
/
Tecido Adiposo Epicárdico
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article