Mass Production of Carbon Nanotube Transistor Biosensors for Point-of-Care Tests.
Nano Lett
; 24(34): 10510-10518, 2024 Aug 28.
Article
em En
| MEDLINE
| ID: mdl-39145617
ABSTRACT
Low-dimensional semiconductor-based field-effect transistor (FET) biosensors are promising for label-free detection of biotargets while facing challenges in mass fabrication of devices and reliable reading of small signals. Here, we construct a reliable technology for mass production of semiconducting carbon nanotube (CNT) film and FET biosensors. High-uniformity randomly oriented CNT films were prepared through an improved immersion coating technique, and then, CNT FETs were fabricated with coefficient of performance variations within 6% on 4-in. wafers (within 9% interwafer) based on an industrial standard-level process. The CNT FET-based ion sensors demonstrated threshold voltage standard deviations within 5.1 mV at each ion concentration, enabling direct reading of the concentration information based on the drain current. By integrating bioprobes, we achieved detection of biosignals as low as 100 aM through a plug-and-play portable detection system. The reliable technology will contribute to commercial applications of CNT FET biosensors, especially in point-of-care tests.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transistores Eletrônicos
/
Técnicas Biossensoriais
/
Nanotubos de Carbono
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article