Microglia's heroic battle against neurodegeneration.
Neuron
; 112(16): 2661-2663, 2024 Aug 21.
Article
em En
| MEDLINE
| ID: mdl-39173587
ABSTRACT
In this issue of Neuron, Chadarevian et al.1 and Munro et al.2 demonstrate how the absence of homeostatic microglia leads to severe neuropathologies, including axonal spheroids, calcifications, myelination abnormalities, and gliosis, associated with leukoencephalopathy and age-related neurodegeneration. Transplantation of healthy microglia can reverse these conditions, opening new avenues for therapeutic research.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Microglia
/
Doenças Neurodegenerativas
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article