Integrating MALDI-TOF Mass Spectrometry with Machine Learning Techniques for Rapid Antimicrobial Resistance Screening of Foodborne Bacterial Pathogens.
Methods Mol Biol
; 2852: 85-103, 2025.
Article
em En
| MEDLINE
| ID: mdl-39235738
ABSTRACT
Although MALDI-TOF mass spectrometry (MS) is considered as the gold standard for rapid and cost-effective identification of microorganisms in routine laboratory practices, its capability for antimicrobial resistance (AMR) detection has received limited focus. Nevertheless, recent studies explored the predictive performance of MALDI-TOF MS for detecting AMR in clinical pathogens when machine learning techniques are applied. This chapter describes a routine MALDI-TOF MS workflow for the rapid screening of AMR in foodborne pathogens, with Campylobacter spp. as a study model.
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Base de dados:
MEDLINE
Assunto principal:
Campylobacter
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Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
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Farmacorresistência Bacteriana
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Aprendizado de Máquina
Idioma:
En
Ano de publicação:
2025
Tipo de documento:
Article