Two-dimensional electrophoresis of cerebrospinal fluid proteins in normal and pathological conditions.
Neurochem Res
; 10(9): 1203-19, 1985 Sep.
Article
em En
| MEDLINE
| ID: mdl-3932893
ABSTRACT
The two-dimensional polyacrylamide gel electrophoresis technique has been adapted for the analysis of human cerebrospinal fluid proteins. Proteins were detected by Coomassie brilliant blue stain and/or by silver stain. Highly reproducible protein patterns were obtained. We analyzed ten normal CSF specimens, thirty pathological CSF specimens and the corresponding sera. We mapped the protein patterns observed by examination of serum/CSF differences and by immunofixation. Preliminary observations on the changes in protein patterns in CSF specimens from patients with neurological disorders are reported.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas do Líquido Cefalorraquidiano
/
Doenças do Sistema Nervoso
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article