Influence of several bacterial and viral vaccines on hepatic drug metabolism in mice.
Methods Find Exp Clin Pharmacol
; 7(9): 481-3, 1985 Sep.
Article
em En
| MEDLINE
| ID: mdl-4079599
ABSTRACT
Pentobarbital-induced sleeping time was found to be significantly prolonged in mice within at least 4 days following either whooping cough, tetanus, rubella or poliomyelitis vaccination. By contrast, barbital-induced sleeping time remained unaffected, These findings provide further evidence of a correlation between inhibition of liver drug metabolizing enzymes and stimulation of the immune response.
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Base de dados:
MEDLINE
Assunto principal:
Pentobarbital
/
Vacina contra Rubéola
/
Toxoide Tetânico
/
Vacina contra Coqueluche
/
Vacina Antipólio de Vírus Inativado
/
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Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article