In vivo studied on the metabolism of dibenzo [c,f]-[1,2] diazepine.
Eur J Drug Metab Pharmacokinet
; 4(2): 67-74, 1979.
Article
em En
| MEDLINE
| ID: mdl-488134
ABSTRACT
The in vivo metabolism of dibenzo [c,f]-[1,2] diazepine (I) was studied after i.p. administration to rats, in order to observe the influence of the heteroatom on the metabolic pathway. Metabolites were separated by chromatography and their structures elucidated by mass spectrometry, by both gas chromatography coupled with mass spectrometry and the direct inlet system. Six metabolites were identified, some of them by direct comparison with authentic samples.
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Base de dados:
MEDLINE
Assunto principal:
Dibenzazepinas
Idioma:
En
Ano de publicação:
1979
Tipo de documento:
Article