[Changes in the secondary and tertiary structure of serum albumin in interactions with ligands of various structures]. / Izmeneniia vtorichnoi i tretichnoi struktury syvorotochnogo al'bumina pri vzaimodeistvii s ligandami razlichnogo stroeniia.

ABSTRACT

High affinity interactions between blood serum albumin and five substances of various chemical structure, exhibiting distinct physiological activity, were accompanied by alterations in the protein tertiary structure, while the albumin secondary structure was involved in conformational transformation after less effective affinity binding.