Gonadoblastoma in a patient with an isodicentric X chromosome.
Clin Genet
; 24(5): 355-8, 1983 Nov.
Article
em En
| MEDLINE
| ID: mdl-6652946
ABSTRACT
Although gonadoblastoma is known to be associated with the presence of a Y chromosome, this case report of a 15-year-old patient with gonadal dysgenesis, gonadoblastoma, and an idic(Xq-) chromosome provides evidence for the occurrence of gonadoblastoma even in the absence of a Y chromosome. A review of previous cases reported to have gonadoblastoma in the absence of a Y chromosome revealed that the presence of some breast development was the common denominator among those patients. Therefore, a patient who presents with gonadal dysgenesis with some breast development, but lacks a Y chromosome may observe as close scrutiny as the patient with gonadal dysgenesis in the presence of a Y chromosome.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Síndrome de Turner
/
Cromossomo X
/
Disgerminoma
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article