Circadian variations of the response of plasma prolactin to brief exposure to ether in the male rat.
Acta Endocrinol (Copenh)
; 94(3): 327-31, 1980 Jul.
Article
em En
| MEDLINE
| ID: mdl-7424475
Male adult rats, supplied with an indwelling chronic intrajugular cannula, were exposed to ether for 1 min at various times of the day. Blood samples were taken before and at regular intervals during 1 h following the ether exposure. Basal plasma prolactin showed a circadian variation. The highest level occurred at 1.00 h, and the lowest values were measured at 10.00 and 13.00 h, while a significant increase was observed at 16.00 h compared to the level at 10.00 and 13.00 h. At all times of the day studied exposure for 1 min to ether increased plasma prolactin for at least 30 min and the magnitude of this response to ether varied with the time of day. At 1.00 h the greatest response was observed, while at 10.00 and 13.00 h the most moderate response was measured. The data indicate that there is either a circadian rhythm in basal prolactin, which may cause a significant circadian variation in the magnitude of the stress response, or there is over the 24 h period a significant variation in stress-sensitivity of the hormone, which may contribute to the circadian variation of 'basal' prolactin.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Prolactina
/
Ritmo Circadiano
/
Éter
/
Etil-Éteres
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article