Neutralization of feline immunodeficiency virus by polyclonal feline antibody: simultaneous involvement of hypervariable regions 4 and 5 of the surface glycoprotein.
J Virol
; 69(8): 5124-7, 1995 Aug.
Article
em En
| MEDLINE
| ID: mdl-7609081
ABSTRACT
Sites involved in antibody-mediated neutralization of feline immunodeficiency virus were mapped by reciprocal exchange of envelope fragments or amino acids between molecular clones of feline immunodeficiency virus with different susceptibilities to neutralization by a polyclonal cat serum. Combinations of mutations within HV-4 or within HV-4 and HV-5 changed the susceptibility of the viruses to neutralizing antibody.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas Virais
/
Glicoproteínas de Membrana
/
Vírus da Imunodeficiência Felina
/
Anticorpos Antivirais
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article