Oral treatment of transmissible gastroenteritis with natural human interferon alpha: a field study.
Vet Immunol Immunopathol
; 45(3-4): 355-60, 1995 Apr.
Article
em En
| MEDLINE
| ID: mdl-7676616
ABSTRACT
During a natural outbreak of transmissible gastroenteritis (TGE), groups of piglets were treated orally for 4 consecutive days with placebo or 1.0, 10.0 or 20.0 international units (IU) natural human interferon alpha (nHuIFN alpha). Piglets that were 1-12 days of age and given 1.0, 10.0 or 20.0 IU nHuIFN alpha had significantly (P < 0.01) greater survival rates than placebo-treated piglets; survival rates were the greater for the highest level of nHuIFN alpha treatment. In contrast, beneficial effects of nHuIFN alpha were not observed in piglets farrowed during the disease outbreak and given nHuIFN alpha within hours of birth. Oral nHuIFN alpha therapy modulates the natural course of high morbidity and mortality commonly seen with TGE.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Surtos de Doenças
/
Interferon-alfa
/
Gastroenterite Suína Transmissível
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article