Cyclosporine A toxicity presenting with acute cerebellar edema and brainstem compression. Case report.
J Neurosurg
; 82(6): 1068-70, 1995 Jun.
Article
em En
| MEDLINE
| ID: mdl-7760181
ABSTRACT
A 38-year-old man receiving cyclosporine A after bilateral lung transplantation for cystic fibrosis presented with cortical blindness, generalized seizures, and cerebellar edema. Progressive brainstem compression necessitated emergency posterior fossa decompression. Replacement of cyclosporine A with an alternative immunosuppressive agent, FK506, was followed by rapid neurological recovery and dramatic resolution of radiographic abnormalities. The etiology, clinical features, and radiographic findings of cyclosporine A neurotoxicity are discussed. The pertinent literature is reviewed.
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Base de dados:
MEDLINE
Assunto principal:
Edema Encefálico
/
Tronco Encefálico
/
Doenças Cerebelares
/
Ciclosporina
/
Síndromes de Compressão Nervosa
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article