[The morphofunctional status of the epithelial spermatogenic layer of the seminiferous tubules in rats in the postresuscitation period]. / Morfofunktsional'noe sostoianie épitelio-spermatogennogo sloia kanal'tsev semennika u krys v postreanimatsionnom periode.

ABSTRACT

The state of spermatogenesis and permeability of the hemato-testicular barrier with respect to acridine orange was studied in mature male rats under conditions of the special longterm hypoxia (12-T min clinical death) and the following postreanimation period. Longterm hypoxia, as well as the complex of endogenous pathological factors of the postreanimation period leads to the degenerative changes of the maturing germ cells (nuclear vacuolization, rough chromatin condensation, cytoplasm enlightenment), their death up to the complete desolation of the certain coiled seminiferous tubules. The appearance of atypical forms of the germ cells (multinuclear elements, cells with giant nuclei) is noted, the disturbance of the synchronism of the germ cells maturation in certain coiled seminiferous tubules took place. Luminescent method revealed the change of the permeability of the hemato-testicular barrier in the certain region of coiled seminiferous tubules with respect to acridine orange.