[Benzimidazole derivatives with antihypertensive and platelet antiaggregant actions]. / Derivati ai benzimidazolului cu actiune antihipertensiva si antiagregant-plachetara.

ABSTRACT

The changing of the chemical structure of 2-benzylbenzimidazole, the active substance of Dibazol (Tromesedan), generated five analogous structures. Two salts of the same active substance have been synthesized in view of improving some of the pharmacological and toxicological features. The results of the anti-AHT and platelet aggregation actions are also presented.