Comparative study of the cellular fatty acids of methicillin-resistant and -susceptible Staphylococcus aureus.
APMIS
; 101(10): 753-61, 1993 Oct.
Article
em En
| MEDLINE
| ID: mdl-8267952
ABSTRACT
The cellular fatty acid compositions of 26 strains of methicillin-resistant Staphylococcus aureus (MRSA) and 17 strains of methicillin-susceptible S. aureus (MSSA) were analyzed by gas-liquid chromatography. The fatty acid compositions of the two groups were very similar with 16 identified components. The major fatty acids were Ci14 = 0, Ci15 = 0, C18 = 0 and C20 = 0. Among these fatty acids, the percentage of the Ci15 = 0 fatty acid component of MRSA strains (11.4 +/- 3.9%) was statistically higher than that of MSSA strains (6.2 +/- 2.4%) (p < 0.001). On the other hand, the percentage of the C20 = 0 fatty acid components of MRSA strains (20.2 +/- 8.8%) was statistically lower than that of MSSA strains (30.7 +/- 10.4%) (p < 0.001). The production of beta-lactamase and beta-hemolysin in both groups' strain was also unrelated to the relative amounts of the fatty acid components. These results indicated a statistical tendency for the percentage fatty acid compositions of the MRSA strains to be quantitatively different from those of the MSSA for both the Ci15 = 0 and C20 = 0 fatty acid components. Analysis of the fatty acid compositions may have an application in the differentiation of MRSA and MSSA strains.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
/
Resistência a Meticilina
/
Ácidos Graxos
/
Meticilina
/
Antibacterianos
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article