Long-term treatment of retinitis pigmentosa with acetazolamide. A pilot study.

The therapeutic effect of long-term treatment with acetazolamide (from 3 weeks to 16 months) of seven patients with retinitis pigmentosa was studied. Improvement in visual acuity was found in almost all the eyes, accompanied by an improvement in the macular threshold in two patients. The therapeutic effect was independent of reduction of macular edema, as judged by fluorescein angiography.