[Modification of adrenergic regulation of heart function under effect of radio-ecological factors within 10-kilometer zone of the accident at Chernobyl nuclear plant]. / Modifikatsiia adrenergicheskoi reguliatsii funktsii serdtsa pod vliianiem radioékologicheskikh uslovii v 10-kilometrovoi zone avarii na ChaES.
Radiats Biol Radioecol
; 33(4): 484-8, 1993.
Article
em Ru
| MEDLINE
| ID: mdl-8401868
Rats kept within the ten-kilometer zone of Chernobyl disaster over a period of 30 days exhibited a decreased heart function response to beta-adrenoreceptor stimulus, reduced density of the receptor structures in cardiomyocytes and their affinity to specific agonists. The number of beta-adrenoreceptors in myocardium cells was restored in 6 months, but their affinity and heart function response to the effect of beta-adrenoagonists remained decreased. No significant changes were observed in regulation influenced indirectly via alpha-adrenoreceptors.
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Base de dados:
MEDLINE
Assunto principal:
Acidentes de Trabalho
/
Receptores Adrenérgicos beta
/
Exposição Ambiental
/
Coração
/
Contração Miocárdica
/
Reatores Nucleares
Idioma:
Ru
Ano de publicação:
1993
Tipo de documento:
Article