Low prevalence of human papillomavirus types 16 and 18 in cervical adenocarcinoma in situ, invasive adenocarcinoma, and glandular dysplasia by polymerase chain reaction.
Mod Pathol
; 6(4): 433-7, 1993 Jul.
Article
em En
| MEDLINE
| ID: mdl-8415587
ABSTRACT
Using the polymerase chain reaction on paraffin blocks for human papillomavirus (HPV) types 16 and 18, a positive result was seen in three of 20 cases of invasive adenocarcinoma, 15 of 36 cases of adenocarcinoma in-situ, and one of five cases of glandular dysplasia of the uterine cervix. Types 16 and 18 were found with equal frequency. In adenocarcinoma in situ there was no age difference between HPV-positive and or HPV-negative cases. Concomitant squamous dysplasia was slightly more frequent in HPV-positive adenocarcinoma in-situ. HPV positivity rates are lower than most of those previously reported. Possible reasons for this are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Infecções Tumorais por Vírus
/
Carcinoma in Situ
/
Adenocarcinoma
/
Displasia do Colo do Útero
/
Neoplasias do Colo do Útero
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article