The effect of cobalt-60 irradiation on the infectivity of Toxoplasma gondii.
Int J Parasitol
; 23(1): 89-93, 1993 Feb.
Article
em En
| MEDLINE
| ID: mdl-8468140
ABSTRACT
Toxoplasma gondii cysts in the tissues of experimentally infected mice and pigs were irradiated with cobalt-60 at various doses and used to infect mice and kittens. Loss of parasite infectivity was confirmed following irradiation whereas control animals inoculated with non-irradiated infected tissues became infected. Experiments were repeated to calculate the minimal effective dose (MED) of irradiation to eradicate parasite infectivity. The MED for the Chinese NT strain and the American ME-49 and TS-2 strains of T. gondii cysts in mouse and pig tissues was approximately 0.6 kGy. The infectivity for mice of NT strain bradyzoites irradiated at a dose of 0.45 kGy was reduced 10,000-fold. Such irradiation may be valuable in practical operations to control T. gondii in pork products.
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Base de dados:
MEDLINE
Assunto principal:
Toxoplasma
/
Toxoplasmose Animal
/
Radioisótopos de Cobalto
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article