Altered gene transcription following brief episodes of coronary occlusions.
Adv Exp Med Biol
; 382: 175-83, 1995.
Article
em En
| MEDLINE
| ID: mdl-8540394
ABSTRACT
This study was designed to elucidate whether previously observed enhanced mRNAs were due to accelerated transcription, enhanced mRNA stability or both mechanisms. We employed the nuclear run-on technique on myocardial nuclei and found the transcriptional induction of several genes, especially nuclear protooncogenes, Ca2+ regulating and heat shock protein genes.
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Base de dados:
MEDLINE
Assunto principal:
RNA Mensageiro
/
Proteínas Nucleares
/
Doença das Coronárias
/
Miocárdio
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article