Relationships between denture base resin cytotoxicity and cell lipid metabolism.
Int J Prosthodont
; 8(6): 580-6, 1995.
Article
em En
| MEDLINE
| ID: mdl-8595119
ABSTRACT
Substances that elute from denture base resins may inhibit cell growth and disrupt various metabolic processes. This study investigated the effects on cell lipid metabolism of eluates from several denture base resins. Cultured oral epithelial cells were exposed in vitro to eluates of discs made from several denture base resins. Lipid metabolism of the cells was measured using isotopic labeling with 14C-acetate. Results demonstrated that the metabolism of several lipid classes found mainly in the cell membrane was altered by the resin eluates. Eluate from one resin caused the appearance of two previously unrecognized classes of lipids. The alterations of the cell lipids and the presence of the previously unrecognized lipids may be the basis for some clinically evident cytotoxic and allergic reactions.
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Base de dados:
MEDLINE
Assunto principal:
Resinas Sintéticas
/
Bases de Dentadura
/
Metabolismo dos Lipídeos
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article