[Clinico-histological scale for identifying preinvasive lesions of the larynx]. / Escala clínico-histológica en el pronóstico de las lesiones preinvasivas de laringe.

ABSTRACT

Preinvasive laryngeal lesions progress to infiltrating carcinoma in 7-15% of cases. Clinical manifestations and histological findings are not reliably predictive of progression. Quantitative cytometry improves predictive effectiveness, but is not a routine procedure. A clinico-histological scale consisting of 13 variables which were combined and used prospectively had a predictive value of 0.8 sensitivity and 0.9 specificity for progression of preinvasive laryngeal lesions.