[A combination chemotherapy with CDDP and 5-FU effective for pulmonary metastases in a case of parotid gland carcinoma].
Gan To Kagaku Ryoho
; 23(8): 1059-62, 1996 Jul.
Article
em Ja
| MEDLINE
| ID: mdl-8687222
ABSTRACT
The patient was a 40-year-old female (154 cm, 45 kg). Several months after receiving radiotherapy, surgery and chemotherapy (Epi-ADR, CDDP, PEP) for an undifferentiated carcinoma of the left parotid gland, she had multiple pulmonary metastases without local recurrence. Following 2 cycles of combination chemotherapy with CDDP (30 mg/1 hr, days 1 approximately 5) and 5-FU (1,000 mg/24 hrs, days 2 approximately 6), most pulmonary nodules disappeared. For the remaining pulmonary nodules, one cycle of combination chemotherapy with 5-FU (850 mg/24 hrs, days 1 approximately 5), leucovorin (9 mg x 3/day, days 1 approximately 5) and CDDP (110 mg/2 hrs, day 7) was added, but further improvement was not obtained on chest CT. Side effects were tolerable in both regimens. It was suggested that the combination chemotherapy with CDDP and 5-FU might be useful for the treatment of advanced parotid gland carcinomas.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Parotídeas
/
Carcinoma
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Neoplasias Pulmonares
Idioma:
Ja
Ano de publicação:
1996
Tipo de documento:
Article