Regional and cellular distribution of spermidine/spermine N1-acetyltransferase (SSAT) mRNA in the rat central nervous system.
Neurosci Lett
; 207(1): 13-6, 1996 Mar 22.
Article
em En
| MEDLINE
| ID: mdl-8710198
ABSTRACT
Spermidine/spermine N1-acetyltransferase (SSAT) is the key enzyme responsible for polyamine interconversion. SSAT mRNA (visualized by in situ hybridization histochemistry) was shown to have a wide but heterogeneous distribution in the central nervous system (CNS) at both regional and cellular levels. The highest labelling was observed in hippocampus (pyramidal and polymorph neurons) and olfactory bulb. Present data suggest that polyamine metabolism in the CNS is not homogeneous but rather that the preferential production of a polyamine species is region- and cell type-specific.
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Base de dados:
MEDLINE
Assunto principal:
Acetiltransferases
/
RNA Mensageiro
/
Sistema Nervoso Central
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article