[Impact of weight difference between donor and recipient on the function of the transplanted kidney]. / Effet de la différence de poids entre donneur et receveur sur la fonction du rein greffé.
Prog Urol
; 6(2): 257-9, 1996 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-8777419
ABSTRACT
OBJECTIVE:
The objective of this retrospective study was to determine whether the difference between the donor's weight (wd) and the recipient's dry weight (wr) could influence the function of renal transplants.METHODS:
Between 1987 and 1994, 185 patients with a mean age of 43.3 years +/- 12 were transplanted with a locally harvested cadaver kidney, corresponding to 120 men (42.2 years +/- 1.4) and 65 women (45 years +/- 12.8). The weight variation between donors and recipients (wd - wr) was 0.06 for men and 0.22 for women. The serum creatinine of recipients at 1 year was 147 mumol +/- 41.7. We used analysis of variance for univariate statistical analysis and multiple linear regression for multivariate analysis.RESULTS:
On univariate analysis, the serum creatinine at 1 and 2 years was significantly higher (p < 0.02 and p < 0.035 respectively) when the donor's weight was 10% lower than the recipient's weight. Multivariate analysis, taking into account the donor's age and sex and the recipient's serum creatinine, confirmed the influence of the donor-recipient weight difference on serum creatinine at 2 years (p0.03), but also the role of the donor's age at 1 and 2 years (p < 0.0001 and p < 0.0004, respectively).CONCLUSION:
In our study, the donor-recipient weight difference was a factor influencing the recipient's serum creatinine at 2 years. The donor's age also influences the recipient's serum creatinine, 1 and 2 years after renal transplantation.
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Base de dados:
MEDLINE
Assunto principal:
Peso Corporal
/
Transplante de Rim
Idioma:
Fr
Ano de publicação:
1996
Tipo de documento:
Article