Compliance to longterm vasoactive intracavernous therapy.

ABSTRACT

From December 1986 to December 1991, 107 patients with organic impotence were advised to intracavernous pharmacological therapy with papaverine. Sixteen patients refused such treatment 91 patients, after the determination of the therapeutical dose, underwent self injection. The follow up was 30-90 months. Thirty-seven patients (40.7%) withdraw the treatment within 3 months 3 patients (3.3%) after losing the partner; 9 (9.9%) for intercurrent disease; 23 (25.3%) were unsatisfied for the therapy; 2 (2.2%) regained spontaneous erections. Complications were local haematomas in 23 (42.6%); prolonged erections in 6 (11.1%); fibrotic changes of the corpora cavernosa in 9 patients (16.7%); liver enzymes changes in 2 (3.7%). The reasons for the low compliance to the intracavernous pharmacological therapy with papaverine were analysed.