Chromosome painting of radiation-induced micronuclei.
Int J Radiat Biol
; 70(4): 393-401, 1996 Oct.
Article
em En
| MEDLINE
| ID: mdl-8862450
ABSTRACT
In this report, in situ hybridization with whole chromosome painting probes was used to paint radiation-induced micronuclei (MN) in three lymphoblastoid cells lines to investigate the frequency of radiation-induced MN. The results obtained for four different chromosomes showed that there was a significant deviation of the numbers of signal-positive MN from that expected on the basis of DNA proportionality. Restriction of the analysis to three chromosomes showed that the deviations arose primarily from chromosome 7, which was underrepresented in the numbers of signal-positive MN in the group of chromosomes studied.
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Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos
/
Micronúcleos com Defeito Cromossômico
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article