Detection of hepatitis G virus (HGV) RNA: clinical characteristics of acute HGV infection.
J Infect Dis
; 175(6): 1302-7, 1997 Jun.
Article
em En
| MEDLINE
| ID: mdl-9180167
ABSTRACT
The role of hepatitis G virus (HGV) infection in acute non-A-E hepatitis was investigated in adults with viral hepatitis. HGV RNA was present in 1 of 28 patients with non-A-E hepatitis but 9 of 22 with hepatitis C (P < .003). HGV RNA-positive patients (HGV-infected and HGV-hepatitis C virus [HCV]-coinfected) developed light-to-moderate jaundice. Clinical and biochemical features of HGV-positive and HCV-positive patients and patients with non-A, non-G hepatitis were similar. Three patients with HGV-HCV coinfection, tested within 18 months after disease onset, have remained HGV RNA-positive but have become HCV RNA-negative. Only 1 non-A-E hepatitis patient was confirmed as being infected with HGV alone, suggesting that HGV is not the main etiologic agent of non-A-E hepatitis. Although HGV RNA was significantly associated with hepatitis C, patients with mixed HCV-HGV infections did not demonstrate a more severe course of disease than did patients with HCV infection.
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Base de dados:
MEDLINE
Assunto principal:
RNA Viral
/
Flaviviridae
/
Hepatite Viral Humana
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article