[Cervical factor in sterility: treatment with intravaginal estriol]. / Fattore cervicale di sterilità: trattamento con estriolo intravaginale.
Minerva Ginecol
; 49(6): 299-302, 1997 Jun.
Article
em It
| MEDLINE
| ID: mdl-9289671
ABSTRACT
BACKGROUND:
The aim of our study was to evaluate the efficacy and tolerability of vaginal estriol in treating the isolated cervical factor.METHODS:
Three different groups of patients were selected at random on the basis of the administered therapy (estriol, ethinyl-estradiol, bromhexine associated with gonadotropins). The patients (thirty in all) came to the Autonomous Sterility Department of the Niguarda Ca' Granda Hospital in Milan during the November 1994-January 1996 period. The following parameters were evaluated cervical score according to Insler, cervical pH; in vivo penetration test (PCT) at third and sixth cycle of treatment; evaluation of the hormonal profile during the ovulatory period of estriol, estradiol, LH and progesterone at the third and sixth cycles of treatment; any possible pregnancy.RESULTS:
On the whole, 23 patients out of 30 (76.6%) had a positive in vivo penetration test. Particularly, a more favourable result was observed in the group to which vaginal estriol was administered as it presented, at treatment end, a positive PCT in 90% of cases. Moreover, always in the latter group, a greater percentage of pregnancies (40%) was observed.CONCLUSIONS:
The obtained results have demonstrated that the drug we have studied can be recommended as a valid therapy for the treatment of the isolated cervical factor of sterility.
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Base de dados:
MEDLINE
Assunto principal:
Estriol
/
Infertilidade Feminina
Idioma:
It
Ano de publicação:
1997
Tipo de documento:
Article