Liver cell cytoplasmic inclusions in experimental porphyrias: their demonstration with the ferric ferricyanide reduction reaction.
Exp Toxicol Pathol
; 49(3-4): 289-93, 1997 Aug.
Article
em En
| MEDLINE
| ID: mdl-9314066
ABSTRACT
In the present paper we describe needle-shaped and granular cytoplasmic inclusions in the liver cells of mice and rats with experimental porphyria biochemically resembling human porphyria cutanea tarda. The inclusions were inconspicuous in routine histological slides. The ferric ferricyanide reduction reaction, however, enabled us to demonstrate their shape and location within the hepatic lobule. Needle-shaped inclusions are considered to represent a structure specifically seen in experimental porphyrias resembling porphyria cutanea tarda. These structures are similar to the inclusions seen in human porphyria cutanea tarda.
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Base de dados:
MEDLINE
Assunto principal:
Porfirias
/
Corpos de Inclusão
/
Modelos Animais de Doenças
/
Ferricianetos
/
Fígado
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article