XDOM, a graphical tool to analyse domain arrangements in any set of protein sequences.
Comput Appl Biosci
; 13(6): 601-8, 1997 Dec.
Article
em En
| MEDLINE
| ID: mdl-9475988
ABSTRACT
MOTIVATION To extract the maximum possible information from a set of protein sequences, its modular organization must be known and clearly displayed. This is important both for structural and functional analysis. RESULTS:
This paper presents an algorithm and a graphical interface called XDOM which performs a systematic analysis of the modular organization of any set of protein sequences. The algorithm is an automatic method to identify putative domains from sequence comparisons. The graphical tool displays the proteins as a set of linked boxes, corresponding to its domains. The method has been tested on a family of bacterial proteins and on whole genomes. It is currently applied to the complete SWISS-PROT database to build the PRODOM database.AVAILABILITY:
XDOM is available free of charge by anonymous ftp¿¿ftp//ftp.toulouse.inra.fr/pub/xdom¿ ¿. The ProDom database can be consulted at ¿¿http//protein.toulouse.inra.fr/prodom.html¿¿.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Gráficos por Computador
/
Software
/
Estrutura Terciária de Proteína
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article