Adenosquamous carcinoma of the tongue: report of a case with histochemical, immunohistochemical, and ultrastructural study and review of the literature.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
; 85(2): 178-84, 1998 Feb.
Article
em En
| MEDLINE
| ID: mdl-9503453
ABSTRACT
A rare case of oral adenosquamous carcinoma in a 78-year-old woman is reported. The tumor occurred in her tongue and metastasized to the submandibular and cervical lymph nodes. Histologically, the tumor showed invasive growth involving the submucosal and muscle layers. Its solid carcinomatous nests exhibited ductal differentiation in the deeper aspects and squamous differentiation toward the surface. Histochemical examination revealed an accumulation of acid mucopolysaccharide in the ductal lumina, and the ductal cells were immunohistochemically positive for carcinoembryonic antigen, epithelial membrane antigen, cancer antigen 15-3 and Ulex europaeus agglutinin I. Ultrastructurally, tonofibrils, desmosomes and numerous cytoplasmic processes were common features of the tumor cells. In addition, true glandular structures and pseudocysts were seen in areas. Clinical features of 13 adenosquamous carcinomas in the literature were analyzed.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Língua
/
Carcinoma Adenoescamoso
/
Lectinas de Plantas
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article