T-cell selection.
Curr Opin Immunol
; 10(2): 214-9, 1998 Apr.
Article
em En
| MEDLINE
| ID: mdl-9602311
ABSTRACT
Major histocompatibility complex (MHC) molecules in the thymus select from the repertoire of germline receptors those that will be most useful in mounting responses to antigen in the periphery. Recent data has shed light on the involvement of self peptides presented by the MHC in this process, and has indicated that a requirement for the constant recognition of 'self' may be essential for T-cell longevity in the periphery.
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Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article