Models for the length distributions of actin filaments: II. Polymerization and fragmentation by gelsolin acting together.
Bull Math Biol
; 60(3): 477-503, 1998 May.
Article
em En
| MEDLINE
| ID: mdl-9608854
ABSTRACT
In a previous paper, we studied elementary models for polymerization, depolymerization, and fragmentation of actin filaments (Edelstein-Keshet and Ermentrout, 1988, Bull. Math. Biol. 60, 449-475). When these processes act together, more complicated dynamics occur. We concentrate on a particular case study, using the actin-fragmenting protein gelsolin. A set of biological parameter values (drawn from the experimental literature) is used in computer simulations of the kinetics of gelsolin-mediated actin filament fragmentation.
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Base de dados:
MEDLINE
Assunto principal:
Actinas
/
Modelos Biológicos
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article