Variability analysis of HIV-1 gp120 V3 region: IV. Distribution functions for intra- and inter-subtype amino acid hamming distances.
J Biomol Struct Dyn
; 15(5): 877-85, 1998 Apr.
Article
em En
| MEDLINE
| ID: mdl-9619510
ABSTRACT
Distribution functions for intra- and inter- HIV-1 V3-loop subtypes amino acid Hamming distances were calculated (850 V3-loop sequences from the Los Alamos HIV-1 Database (1996) were used). These functions have pronounced bell-like shape. Such shapes of the histograms for HIV-1 V3 intra- and inter-subtype distriutions are discussed to confirm the applicability of different hierarchical cluster procedures for HIV-1 V3 classification. Two-mode distribution for the subtype E could sertificate that this subtype includes two thinner taxons.
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Base de dados:
MEDLINE
Assunto principal:
Fragmentos de Peptídeos
/
Computação Matemática
/
Proteína gp120 do Envelope de HIV
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article