[Comparison of 51Cr-EDTA with 99m-Tc-DTPA slope clearance for estimation of glomerular filtration rate using the one compartment model]. / Vergleich der 51Cr-EDTA-mit der 99mTc-DTPA-Slope-Clearance zur Bestimmung der glomerulären Filtrationsrate nach dem Ein-Kompartiment-Modell.
Nuklearmedizin
; 37(4): 124-8, 1998 Jun.
Article
em De
| MEDLINE
| ID: mdl-9650211
ABSTRACT
AIM:
Of this study is to determine the relationship between 51Cr-EDTA and 99mTc-DTPA slope clearance applying the "one-compartment model".METHODS:
The "one-compartment model" was chosen to calculate and to compare the glomerular filtration rates of 25 patients with normal and pathological creatinin values after injection of 51Cr-EDTA and 99mTc-DTPA simultaneously.RESULTS:
The two clearance values correlated well (r = 0.996), and the 99mTc-DTPA clearance was systematically higher (28%). The 99mTc-DTPA was calculated and compared after taking three plasma samples. Taking two samples, only minor differences were seen and the correlation was high (r = 0.992).CONCLUSION:
The results of this study encouraged us to adopt the use of 99mTc-DTPA instead of 51Cr-EDTA in determining the glomerular filtration applying the "one-compartment model" in slope with two plasma samples.
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Base de dados:
MEDLINE
Assunto principal:
Radioisótopos de Cromo
/
Pentetato de Tecnécio Tc 99m
/
Compostos Radiofarmacêuticos
/
Taxa de Filtração Glomerular
/
Modelos Biológicos
Idioma:
De
Ano de publicação:
1998
Tipo de documento:
Article