Prolactin and growth hormone signal transduction in lymphohaemopoietic cells.
Cell Mol Life Sci
; 54(10): 1067-75, 1998 Oct.
Article
em En
| MEDLINE
| ID: mdl-9817985
ABSTRACT
The peptide hormones, prolactin (PRL) and growth hormone (GH), are known to regulate numerous target tissues. Among such targets are cells of the immune system, including T cells, B cells, macrophages and natural killer cells. We have cloned a panel of PRL- and GH-inducible T cell genes for use in studies to understand how these hormones through the expression of these genes modulate the biology of immune function cells. This article focuses on the signalling pathways emanating from the PRL receptor (PRL-R) and GH receptor (GH-R), and the expression of PRL-inducible target genes.
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Base de dados:
MEDLINE
Assunto principal:
Prolactina
/
Hormônio do Crescimento
/
Linfócitos B
/
Células Matadoras Naturais
/
Linfócitos T
/
Transdução de Sinais
/
Regulação da Expressão Gênica
/
Macrófagos
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article