Rash, fever, and chills after intravenous fluorescein angiography.

ABSTRACT

PURPOSE: To report a previously unreported complication associated with intravenous injection of fluorescein dye. METHOD: Case report. A 75-year-old man developed a unique complication after intravenous injection of fluorescein dye for angiography. RESULTS: Two hours after receiving an intravenous injection of fluorescein for angiography, the patient developed a fever, rash, and chills. Admission to a hospital and careful systemic evaluation determined that this reaction was a noninfectious allergic response to intravenous fluorescein dye injection. CONCLUSION: A delayed allergic response to intravenous fluorescein dye injection can occur.