Azithromycin for ocular toxoplasmosis.
Br J Ophthalmol
; 82(11): 1306-8, 1998 Nov.
Article
em En
| MEDLINE
| ID: mdl-9924338
ABSTRACT
AIMS:
To investigate the efficacy of azithromycin in patients with ocular toxoplasmosis.METHODS:
11 immunocompetent patients with ocular toxoplasmosis were treated with azithromycin (500 mg the first day, followed by 250 mg/day for 5 weeks). Ocular and systemic examinations were performed during active retinitis episodes and all patients were followed for at least 1 year.RESULTS:
The intraocular inflammation disappeared within 4 weeks in seven patients, including two cases with progressive retinitis despite previous treatment with pyrimethamine, sulphadiazine, and folinic acid. Recurrence of retinitis occurred in three patients (27%) within the first year of follow up. No systemic side effects of azithromycin were encountered.CONCLUSION:
These results indicate that although azithromycin cannot prevent recurrent disease it may be an effective alternative for patients with ocular toxoplasmosis who cannot tolerate standard therapies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Toxoplasmose Ocular
/
Azitromicina
/
Antibacterianos
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article