Pharmacotherapeutic problems and pharmaceutical interventions in critical hospitalized patients / Problemas farmacoterapêuticos e intervenções farmacêuticasa em pacientes críticos hospitalizados

ABSTRACT

A critical patient is one who is seriously ill and needs a multi-professional team dedicated to their intensive care. Becauseample prescription medication is involved, such patients are more susceptible to pharmacotherapeutic problems.The purpose of the study was to evaluate the profile of pharmacotherapeutic problems (PP) and pharmaceuticalinterventions (PI) performed by residents of a Multi-professional Residency Program in Critical Patient Care. This wasa descriptive and quantitative study carried out by evaluating pharmaceutical care records completed by residentscaring for critical patients who were hospitalized at a teaching hospital in Campo Grande, MS, from March to August2016. The study was approved by the Ethics Committee of the Federal University of Mato Grosso do Sul, opinionNo. 1,371,325. The drug prescriptions of 60 patients with an average age of 60.2 (± 16.6) years were evaluated. Atotal of 218 PP were identified, with an average of 3.6 (± 1.4) PP per participant. Twenty-six patients (43.3%) had 4or more PP. The most frequent were medication not available due to lack of stock (n=48; 22%), existence of a moreadequate/available therapeutic alternative (n=37; 17%), and need for laboratory monitoring (n=22; 10.1%). A total of154 PI, 2.56 (± 0.7) per participant, were performed. The most frequent were indication of a more adequate/availabletherapeutic alternative (n=37; 24%), orientation on drug-drug incompatibility (n=16, 10.4%), and orientation on drugdruginteraction (n=12; 7.8%). Most PI (n=133; 86.4%) were directed to physicians and were accepted without change(n=96; 62%). The results showed a high incidence of PP and PI in critical patients(AU)