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3MOTIF: visualizing conserved protein sequence motifs in the protein structure database.

Bennett, Steven P; Nevill-Manning, Craig G; Brutlag, Douglas L.
Bioinformatics ; 19(4): 541-2, 2003 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-12611811


3MOTIF is a web application that visually maps conserved sequence motifs onto three-dimensional protein structures in the Protein Data Bank (PDB; Berman et al., Nucleic Acids Res., 28, 235-242, 2000). Important properties of motifs such as conservation strength and solvent accessible surface area at each position are visually represented on the structure using a variety of color shading schemes. Users can manipulate the displayed motifs using the freely available Chime plugin.