Plasma membrane profiling during enterohemorrhagic <i>E. coli</i> infection reveals that the metalloprotease StcE cleaves CD55 from host epithelial surfaces.

Furniss, R Christopher D; Low, Wen Wen; Mavridou, Despoina A I; Dagley, Laura F; Webb, Andrew I; Tate, Edward W; Clements, Abigail

Plasma membrane profiling during enterohemorrhagic E. coli infection reveals that the metalloprotease StcE cleaves CD55 from host epithelial surfaces.

Furniss, R Christopher D; Low, Wen Wen; Mavridou, Despoina A I; Dagley, Laura F; Webb, Andrew I; Tate, Edward W; Clements, Abigail.

Afiliación

Furniss RCD; From the MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, SW7 2AZ United Kingdom.
Low WW; From the MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, SW7 2AZ United Kingdom.
Mavridou DAI; From the MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, SW7 2AZ United Kingdom.
Dagley LF; Walter and Eliza Hall Institute of Medical Research, Melbourne 3052, Australia.
Webb AI; Department of Medical Biology, University of Melbourne, Melbourne 3050, Australia, and.
Tate EW; Walter and Eliza Hall Institute of Medical Research, Melbourne 3052, Australia.
Clements A; Department of Medical Biology, University of Melbourne, Melbourne 3050, Australia, and.

J Biol Chem ; 293(44): 17188-17199, 2018 11 02.

Article en En | MEDLINE | ID: mdl-30190327

Asunto(s)

Antígenos CD55/metabolismo; Membrana Celular/metabolismo; Células Epiteliales/metabolismo; Infecciones por Escherichia coli/metabolismo; Escherichia coli O157/enzimología; Proteínas de Escherichia coli/metabolismo; Metaloendopeptidasas/metabolismo; Antígenos CD55/genética; Membrana Celular/genética; Membrana Celular/microbiología; Células Epiteliales/microbiología; Infecciones por Escherichia coli/genética; Infecciones por Escherichia coli/microbiología; Escherichia coli O157/genética; Escherichia coli O157/fisiología; Proteínas de Escherichia coli/genética; Células HeLa; Humanos; Enfermedades Intestinales/genética; Enfermedades Intestinales/metabolismo; Enfermedades Intestinales/microbiología; Metaloendopeptidasas/genética; Neutrófilos/metabolismo; Neutrófilos/microbiología

Palabras clave

CD55; EHEC; EPHA2; StcE; cell surface; host-pathogen interaction; infection; metalloprotease; neutrophil; proteomics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Metaloendopeptidasas / Membrana Celular / Antígenos CD55 / Escherichia coli O157 / Proteínas de Escherichia coli / Células Epiteliales / Infecciones por Escherichia coli Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article

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